{
    "_full_name": "Lennart Kester", 
    "_id": "u_is96yWC", 
    "affiliation_name": "Prinses M\u00e1xima Centrum voor Kinderoncologie", 
    "affiliation_role_title": "Molecular pathologist", 
    "badges": [
        {
            "context": "This level of availability puts you in the top 5% of researchers.", 
            "created": "2026-06-22T00:57:11.119071+00:00", 
            "description": "77% of your research is free to read online.", 
            "display_name": "Open Access", 
            "extra_description": null, 
            "group": "openness", 
            "id": "72zJLFbjyf", 
            "importance": 0.9, 
            "name": "percent_fulltext", 
            "orcid_id": null, 
            "percentile": 0.95, 
            "show_in_ui": true, 
            "sort_score": 0.855, 
            "support_finale": null, 
            "support_intro": "Even better, 33% of your papers are published under a fully Open license like CC-BY, making them available for a wide range of reuse (not just reading). Learn more about why this is important at <a href=\"http://sparcopen.org/our-work/howopenisit/\">HowOpenIsIt.</a>", 
            "support_items": null, 
            "value": 77.8
        }, 
        {
            "context": "This level of availability puts you in the top 3% of researchers.", 
            "created": "2026-06-22T00:57:11.119589+00:00", 
            "description": "33% of your research has a CC-BY, CC0, or public domain license.", 
            "display_name": "Open License", 
            "extra_description": null, 
            "group": "openness", 
            "id": "eiVCdGMcAA", 
            "importance": 0.8, 
            "name": "open_license", 
            "orcid_id": null, 
            "percentile": 0.97, 
            "show_in_ui": true, 
            "sort_score": 0.776, 
            "support_finale": null, 
            "support_intro": null, 
            "support_items": null, 
            "value": 33.300000000000004
        }
    ], 
    "campaign": null, 
    "claimed_at": null, 
    "coauthors": null, 
    "created": "2026-06-22 00:57:10.137537+00:00", 
    "depsy_id": null, 
    "email": null, 
    "family_name": "Kester", 
    "first_name": "Lennart", 
    "fresh_orcid": false, 
    "given_names": "Lennart", 
    "id": "u_is96yWC", 
    "mendeley": {
        "country_percent": {}, 
        "job_title_percent": {}, 
        "mendeley_url": null, 
        "percent_of_products": 0.0, 
        "readers": 0, 
        "subdiscipline_percent": {}
    }, 
    "num_mentions": 0, 
    "num_orcid_products": 18, 
    "num_posts": 0, 
    "num_twitter_followers": null, 
    "orcid_id": "0000-0002-8259-9971", 
    "overview_badges": [
        {
            "context": "This level of availability puts you in the top 5% of researchers.", 
            "created": "2026-06-22T00:57:11.119071+00:00", 
            "description": "77% of your research is free to read online.", 
            "display_name": "Open Access", 
            "extra_description": null, 
            "group": "openness", 
            "id": "72zJLFbjyf", 
            "importance": 0.9, 
            "name": "percent_fulltext", 
            "orcid_id": null, 
            "percentile": 0.95, 
            "show_in_ui": true, 
            "sort_score": 0.855, 
            "support_finale": null, 
            "support_intro": "Even better, 33% of your papers are published under a fully Open license like CC-BY, making them available for a wide range of reuse (not just reading). Learn more about why this is important at <a href=\"http://sparcopen.org/our-work/howopenisit/\">HowOpenIsIt.</a>", 
            "support_items": null, 
            "value": 77.8
        }, 
        {
            "context": "This level of availability puts you in the top 3% of researchers.", 
            "created": "2026-06-22T00:57:11.119589+00:00", 
            "description": "33% of your research has a CC-BY, CC0, or public domain license.", 
            "display_name": "Open License", 
            "extra_description": null, 
            "group": "openness", 
            "id": "eiVCdGMcAA", 
            "importance": 0.8, 
            "name": "open_license", 
            "orcid_id": null, 
            "percentile": 0.97, 
            "show_in_ui": true, 
            "sort_score": 0.776, 
            "support_finale": null, 
            "support_intro": null, 
            "support_items": null, 
            "value": 33.300000000000004
        }
    ], 
    "percent_fulltext": 0.778, 
    "percent_open_license": 0.333, 
    "picture": "https://www.gravatar.com/avatar/?s=110&d=mm", 
    "products": [
        {
            "_title": "Molecular Features Associated with a High-Risk Clinical Course in Neuroblastomas Initially Diagnosed as Non-High-Risk", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.3390/cancers18020235", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.mdpi.com/2072-6694/18/2/235/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "y42mmA253Z", 
            "journal": "Cancers", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Molecular Features Associated with a High-Risk Clinical Course in Neuroblastomas Initially Diagnosed as Non-High-Risk", 
            "url": "http://doi.org/10.3390/cancers18020235", 
            "year": "2026"
        }, 
        {
            "_title": "<i>DICER1</i> Syndrome: What Do We Know of the Pathogenetic Mechanisms?", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.3390/cancers17172885", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.mdpi.com/2072-6694/17/17/2885/pdf?version=1756808932", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "BVLEWV4EJN", 
            "journal": "Cancers", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "<i>DICER1</i> Syndrome: What Do We Know of the Pathogenetic Mechanisms?", 
            "url": "http://doi.org/10.3390/cancers17172885", 
            "year": "2025"
        }, 
        {
            "_title": "CCN2 Aggravates the Immediate Oxidative Stress&ndash;DNA Damage Response following Renal Ischemia&ndash;Reperfusion Injury", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.3390/antiox10122020", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.mdpi.com/2076-3921/10/12/2020/pdf?version=1639984956", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "utFKCkDZDH", 
            "journal": "Antioxidants", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "CCN2 Aggravates the Immediate Oxidative Stress&ndash;DNA Damage Response following Renal Ischemia&ndash;Reperfusion Injury", 
            "url": "http://doi.org/10.3390/antiox10122020", 
            "year": "2021"
        }, 
        {
            "_title": "Loss of H3K27me3 occurs in a large subset of embryonal rhabdomyosarcomas: Immunohistochemical and molecular analysis of 25 cases", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.anndiagpath.2021.151735", 
            "events_last_week_count": 0, 
            "fulltext_url": null, 
            "genre": "article", 
            "has_fulltext_url": false, 
            "id": "pDWqwCyKNQ", 
            "journal": "Annals of Diagnostic Pathology", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Loss of H3K27me3 occurs in a large subset of embryonal rhabdomyosarcomas: Immunohistochemical and molecular analysis of 25 cases", 
            "url": "http://doi.org/10.1016/j.anndiagpath.2021.151735", 
            "year": "2021"
        }, 
        {
            "_title": "Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.stem.2020.02.008", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S1934590920300618/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "hZatfvZp8N", 
            "journal": "Cell stem cell", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer", 
            "url": "http://doi.org/10.1016/j.stem.2020.02.008", 
            "year": "2020"
        }, 
        {
            "_title": "An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/s41591-019-0422-6", 
            "events_last_week_count": 0, 
            "fulltext_url": null, 
            "genre": "article", 
            "has_fulltext_url": false, 
            "id": "p5jpYSXUoj", 
            "journal": "Nature Medicine", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity", 
            "url": "http://doi.org/10.1038/s41591-019-0422-6", 
            "year": "2019"
        }, 
        {
            "_title": "Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/s41467-018-04893-3", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.nature.com/articles/s41467-018-04893-3.pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "pqpkQHTssW", 
            "journal": "Nature Communications", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta.", 
            "url": "http://doi.org/10.1038/s41467-018-04893-3", 
            "year": "2018"
        }, 
        {
            "_title": "Single-Cell Transcriptomics Meets Lineage Tracing.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.stem.2018.04.014", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S1934590918301760/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "t9mizyS6pb", 
            "journal": "Cell stem cell", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Single-Cell Transcriptomics Meets Lineage Tracing.", 
            "url": "http://doi.org/10.1016/j.stem.2018.04.014", 
            "year": "2018"
        }, 
        {
            "_title": "Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.stemcr.2018.02.005", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S2213671118300961/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "Z96T9d23UJ", 
            "journal": "Stem Cell Reports", 
            "license": "cc-by-nc-nd", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.", 
            "url": "http://doi.org/10.1016/j.stemcr.2018.02.005", 
            "year": "2018"
        }, 
        {
            "_title": "Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.celrep.2016.11.069", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S2211124716316436/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "CBPzwAkznP", 
            "journal": "Cell Reports", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.", 
            "url": "http://doi.org/10.1016/j.celrep.2016.11.069", 
            "year": "2016"
        }, 
        {
            "_title": "Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.celrep.2016.02.034", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S2211124716301371/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "Bek2GVNrEF", 
            "journal": "Cell Reports", 
            "license": "cc-by-nc-nd", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity.", 
            "url": "http://doi.org/10.1016/j.celrep.2016.02.034", 
            "year": "2016"
        }, 
        {
            "_title": "Single-cell messenger RNA sequencing reveals rare intestinal cell types.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/nature14966", 
            "events_last_week_count": 0, 
            "fulltext_url": null, 
            "genre": "article", 
            "has_fulltext_url": false, 
            "id": "KKE6E3TTd7", 
            "journal": "Nature", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Single-cell messenger RNA sequencing reveals rare intestinal cell types.", 
            "url": "http://doi.org/10.1038/nature14966", 
            "year": "2015"
        }, 
        {
            "_title": "DAZL regulates Tet1 translation in murine embryonic stem cells.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.15252/embr.201540538", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://pure.knaw.nl/portal/en/publications/39f28298-590f-46f6-8d04-678f5fdd8fc6", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "wvCE9VAuee", 
            "journal": "EMBO Reports", 
            "license": "other-oa", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "DAZL regulates Tet1 translation in murine embryonic stem cells.", 
            "url": "http://doi.org/10.15252/embr.201540538", 
            "year": "2015"
        }, 
        {
            "_title": "Prospective derivation of a living organoid biobank of colorectal cancer patients.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1016/j.cell.2015.03.053", 
            "events_last_week_count": 0, 
            "fulltext_url": "http://www.cell.com/article/S0092867415003736/pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "BhC3mpPLWy", 
            "journal": "Cell", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Prospective derivation of a living organoid biobank of colorectal cancer patients.", 
            "url": "http://doi.org/10.1016/j.cell.2015.03.053", 
            "year": "2015"
        }, 
        {
            "_title": "Integrated genome and transcriptome sequencing of the same cell.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/nbt.3129", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/4374170", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "nN5CCeCyv4", 
            "journal": "Nature Biotechnology", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Integrated genome and transcriptome sequencing of the same cell.", 
            "url": "http://doi.org/10.1038/nbt.3129", 
            "year": "2015"
        }, 
        {
            "_title": "Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/ncomms6728", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.nature.com/articles/ncomms6728.pdf", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "DN9PD4FkTi", 
            "journal": "Nature Communications", 
            "license": "cc-by", 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2.", 
            "url": "http://doi.org/10.1038/ncomms6728", 
            "year": "2014"
        }, 
        {
            "_title": "Validation of noise models for single-cell transcriptomics.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/nmeth.2930", 
            "events_last_week_count": 0, 
            "fulltext_url": null, 
            "genre": "article", 
            "has_fulltext_url": false, 
            "id": "m6CtUBxb2U", 
            "journal": "Nature Methods", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Validation of noise models for single-cell transcriptomics.", 
            "url": "http://doi.org/10.1038/nmeth.2930", 
            "year": "2014"
        }, 
        {
            "_title": "Differential proliferation rates generate patterns of mechanical tension that orient tissue growth.", 
            "altmetric_id": null, 
            "altmetric_score": 0, 
            "authors": null, 
            "doi": "10.1038/emboj.2013.197", 
            "events_last_week_count": 0, 
            "fulltext_url": "https://www.ncbi.nlm.nih.gov/pmc/articles/3817460", 
            "genre": "article", 
            "has_fulltext_url": true, 
            "id": "PJZttxAeYS", 
            "journal": "The EMBO Journal", 
            "license": null, 
            "mendeley": {
                "country_percent": {}, 
                "job_title_percent": {}, 
                "mendeley_url": null, 
                "readers": 0, 
                "subdiscipline_percent": {}
            }, 
            "num_mentions": 0, 
            "num_posts": 0, 
            "orcid_id": null, 
            "posts": [], 
            "sources": [], 
            "title": "Differential proliferation rates generate patterns of mechanical tension that orient tissue growth.", 
            "url": "http://doi.org/10.1038/emboj.2013.197", 
            "year": "2013"
        }
    ], 
    "promos": null, 
    "sources": [], 
    "subscores": [
        {
            "display_name": "buzz", 
            "name": "buzz"
        }, 
        {
            "display_name": "engagement", 
            "name": "engagement"
        }, 
        {
            "display_name": "openness", 
            "name": "openness"
        }, 
        {
            "display_name": "fun", 
            "name": "fun"
        }
    ], 
    "twitter": null, 
    "updated": "2026-06-22T00:57:11.124176+00:00"
}